J.EXPERIMENTAL & CLINICAL MEDICINE
2011. ¹ 5.
1. Burkadze N., Isakadze A., Noniashvili M.
Correction non-modifiable risk-faktors in adults
J. Experimental and Clinical Medicine, 2011, 5, pp.8-11
The Science Academy of preventive medicine of Georgia
Identification of arterial hypertension, overweight, low physical activity, smoking, alcohol and salt over usage, psycho-emotional stress and drug addiction in the same populations. Stratification of examined populations to risk-groups (low, middle and high risk groups). Development and implementation of differentiated preventive intervention programs for middle and high risk groups.
Development of measures for healthy lifestyle principles promotion (development and distribution of educational literature taking into consideration specific features of the population, trainings with active participation of adults, information and involvement of mass media).
Dynamic supervision of the whole population (with examination of focus groups) and implementing preventive activities.
Assessment of regular dynamic supervision and active intervention significance for risk-factor correction (repetitive testing of population, examination to detect risk factor frequency).
Development of the model for youth education on healthy lifestyle principles and its recommendation for implementation in public health
2. Isakadze A., Burkadze N., Noniashvili M., Robakidze T.
Epidemiological survey for chronic biliary tract diseases
J. Experimental and Clinical Medicine, 2011, 5, pp.11-14
The Academy of Science Preventive Medicine, Tbilisi, Georgia
The incidence of the right hypochondrium syndrome was studied among 5038 population aged 20 to 59 years in Tbilisi. The relationship was defined between this syndrome and some risk factors of cholelithiasis. The term right hypochondrium syndrome (RHS) was applied with a purpose of specifying a trait marking certain diseases including different cholecystopathies. The RHS was detected in 3,54 of men and 9,6% of women. The RHS incidence correlated with the following risk factors: female sex, age (40-59 years), overweight, and upset lipid metabolism. The subjects with the RHS are to be subjected to further diagnostic examinations and prophylactic and treatment measures aimed against obesity, upset lipid metabolism and cholelithiasis.
3. SAHAKYAN N. A.
HEART RATE VARIABILITY AND HISTOCHEMICAL STUDY OF BRAIN CORTEX AT IMMOBILIZATION STRESS
J. Experimental and Clinical Medicine, 2011, 5, pp.14-18
Armenian State Pedagogical University department human and animal physiology,Yerevan
Immobilization stress is the psycho-emotional stress (with weak physical and strong psychological components).The purpose of this research was the study of peculiarities of functional state in rats in the dynamics of post-immobilization stress. The comparative analysis of the results obtained in stressed rats through the methods of MA (mathematical analysis) VHR (variability of heart rate) detected significant changes in functional state of animals. During 7 days there was no tendency to return to the studied indicators to normal: even in this period the animals were in the state of stress reaction. Sustained psycho-emotional tension can favor the development of stressful diseases.
4. kiladze N., Shulaia t., korsantia n.
comparative analysis of efficiency of peeling in the treatment
of melasma
J. Experimental and Clinical Medicine, 2011, 5, pp.18-24
Tbilisi State Medical University, Medical Center “Marjani XXI”, Georgia
Melasma is a very common cutaneous disorder which affects all races, but there is a particular prominence among females during their late third decade of life. Many depigmenting agents and other therapies are used for treatment of melasma, in the form of monotherapy or combined therapy, but the results are often unsatisfactory. In the present trial, including 20 patients with epidermal type of melasma, was studied the tolerance and effectiveness of alfa-beta and retinol professional peeling of Holy Land Cosmetics in comparison with results of chemical peeling with Jessner solution. Evaluation of skin condition was done in accordance with MASI score before and after treatment. After a follow-up period of six months, the MASI score was found to be reduced in 73,2% in the case of peeling by Holy Land product and 30,4% in the case of Jessner solution. The results of the trial gives us a possibility to recommend the above mentioned Holy Land product for successful treatment of epidermal type of melasma.
5. PARULAVA TS., CHKHAIDZE M., GOTUA T., KHURTSILAVA I.
PAIN PREVENTION, CONTROL AND MANAGEMENT IN NEONATES
J. Experimental and Clinical Medicine, 2011, 5, pp.24-28
Children New Clinic, Tbilisi, Georgia
From 24 weeks post-conceptional age all neurotransmitters and receptors associated with pain modulation are present and responsive, thus fetus and newborn can feel pain. Pain can cause immediate adverse physiologic effects (tachycardia, blood pressure changes, hypoxemia, tachypnea, increased release of cathecholamins, steroids, glucagon) and long term behavioral changes.
For any potentially painful intervention in neonates pain assessment using scoring stools (NIPS, CRIES, PIPP, N-PASS) and pain management or analgesia should be considered. Guidelines for pain management are: prevention or minimization of painful procedures; analgesia before painful procedures; non-pharmacologic or pharmacologic interventions.
6. Mkrtchyan A.G.
PSYCHOTIC FORM OF RESIDUAL CONDITION IN MANIFESTED PROGREDIENT
FORMS OF SCHIZOPHRENIA (1st notification)
J. Experimental and Clinical Medicine, 2011, 5, pp.28-34
Department of Psychiatry at Yerevan M.Heratci State Medical University. Armenia
The study applied clinical psychopathological, clinical cathamnestic and psychometric testing approaches to examine 243 institutionalized chronic patients with manifested progredient forms of schizophrenia in residual phase of the disease.
While differentiating the forms of the outcomes, the study found psychotic form of residual condition in 9.5%, the form with reduced positive symptoms in 35.8%, deficit form in 42.0% and outcome in the form of clinical recovery in 12.8% of the investigated cases. Different clinical types of hallucinatory-delusional disorders were observed among the patients with psychotic form of the residual condition. The study classified the patients into the hallucinatory (30.4% of the all psychotic conditions), hallucinatory paranoid (13%), hallucinatory paraphrenic (13%), paranoid (26.1%) and paraphrenic (17.5%) forms of the residual condition based on the predominance of the psychopathological syndromes.
7. Mkrtchyan A.G.
RESIDUAL CONDITION WITH REDUCED POSITIVE DISORDERS IN MANIFESTED PROGREDIENT FORMS OF SCHIZOPHRENIA (2nd notification)
J. Experimental and Clinical Medicine, 2011, 5, pp.34-40
Department of Psychiatry at Yerevan M.Heratci State Medical University, Armenia
The study applied clinical psychopathological, clinical cathamnestic and psychometric testing approaches to examine 243 institutionalized chronic patients with manifested progredient forms of schizophrenia in residual phase of the disease.
While differentiating the forms of the outcomes, the study found psychotic form of residual condition in 9.5%, the form with reduced positive symptoms in 35.8%, deficit form in 42.0% and outcome in the form of clinical recovery in 12.8% of the investigated cases. The study observed reduced speech disorders in 18.4%, reduced hallucinations and delusions in 34.5%, reduced formal disorder of the thoughts in 47.1% of cases among the patients with the outcome of the reduced positive disorders.
8. varshanidze N., Dolidze K., Diasamidze I., Turmanidze N.
Ginkgo biloba -valuable decoration and medicinal plant
J. Experimental and Clinical Medicine, 2011, 5, pp.40-41
Shota Rustaveli State University, Batumi, Georgia
In the article are represented Ginkgo biloba botanical characteristic and phitochemical analyses. Now preparations of Ginkgo biloba are considered as one of the most used medical products. For finding-out of an opportunity of use of leaves of Ginkgo biloba, growing in Georgia as medicinal raw material, we start works on cultivation of the given plant. It was started the opportunity of cultivation and prospect of creation of plantation of this valuable plant.
9. Diasamidze I., Varshanidze N., Turmanidze N.
Medicinal plants of oak forest of Adjara
J. Experimental and Clinical Medicine, 2011, 5, pp.41-42
Shota Rustaveli State University, Batumi, Georgia
The inventory, carried out in the environs of Adjara oak forest has revealed that the medicinal plants include 21 families and 81 species of 70genera. According to the number species the leading families are: Lamiaceae-11 Asteraceae-8, Rosaceae-6, Solanaceae-5, Convallariaceae-4, are endemic - 2 species. Some of them are recorded as the most threatened taxa or being under risk of extinction. On the one hand, it is conditioned by destruction of natural habitat and on the other hand, they are intensively used for different economic needs. So, in situ and ex situ conservation of these plants becomes indispensable.